Genotype1 contains viruses from the Philippines, Thailand and Sri Lanka genotype2 consists of viruses from Indonesia, Tahiti, the Caribbean Islands Puerto Rico, Dominica and Central and South America.. Nucleotide sequences of the envelope protein genes of geographically and temporally distinct dengue DEN4 viruses were determined. Alignment of nucleic acid sequences followed by parsimony analysis generated phylogenetic trees, which indicated that geographically independent evolution of DEN4 viruses had occurred. Nucleic acid sequence comparison revealed that the identity among the DEN4 viruses was greater than 92.
Alignment of nucleic acid sequences followed by parsimony analysis generated phylogenetic trees, which indicated that geographically independent evolution of DEN4 viruses had occurred. Nucleic acid sequence comparison revealed that the identity among the DEN4 viruses was greater than 92. Genotype1 contains viruses from the Philippines, Thailand and Sri Lanka genotype2 consists of viruses from Indonesia, Tahiti, the Caribbean Islands Puerto Rico, Dominica and Central and South America.. DEN4 viruses were separated into two genetically distinct subtypes genotypes. Similarity among deduced amino acids was between and 100 in cases identical amino acid substitutions occurred among viruses from similar geographical regions.
Tags: evolution, nucleotide