For an explanation of how the

Posted by Ellie on Jun 9, 2008 in Proteomics | 0 comments

To really understand biological processes, we need to understand how proteins function in and around cells since they are the functioning units, says Hanno Steen, director of the Proteomics Center at Childrens at Hospital Steen and Steen Lab Introduction to Proteomics Go to Childrens interactive Guide to Sequencing and Identifying Proteins.

Childrens Hospital Research Childrens Hospital Labs Introduction to Proteomics Go to Childrens interactive Guide to Sequencing and Identifying ProteinsA stepbystep explanation of how to identify and sequence proteins using 2D electrophoresis, mass spectroscopy and informatics. And the reason is clear. Thats obviously simple explanation of the process. By identifying and sequencing these smaller pieces, researchers can then determine the identity of the protein they make up. Another challenge is that amino acids the base units of proteins are so small. The task of studying the proteome has its share of challenges.

By identifying and sequencing these smaller pieces, researchers can then determine the identity of the protein they make up. How are researchers able to determine the sequence of amino acids that make up proteins? One way is by separating the proteins, breaking them up into smaller pieces, and using mass spectrometers to, in effect, weigh each amino acid. One involves the sheer number of proteins that need to be identified.

This is far beyond the reach of even the powerful microscopes. How are researchers able to determine the sequence of amino acids that make up proteins?

Thats obviously simple explanation of the process. How are researchers able to determine the sequence of amino acids that make up proteins? One way is by separating the proteins, breaking them up into smaller pieces, and using mass spectrometers to, in effect, weigh each amino acid. By identifying and sequencing these smaller pieces, researchers can then determine the identity of the protein they make up. Requires Flash plugin. The BasicsStart here if you need refresher on what proteins do, what theyre made of, and how genes code for proteins.

How are researchers able to determine the sequence of amino acids that make up proteins? One way is by separating the proteins, breaking them up into smaller pieces, and using mass spectrometers to, in effect, weigh each amino acid. For an explanation of how the genome is decoded, go to NOVAs Sequence for Yourself..
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