With the progress of

References At the same time, it is misleading to believe that only system structure, such as network topologies, is important without paying sufficient attention to diversities and functionalities of components. Systems biology is in its infancy, but this is the area that we believe to be the main stream in biological sciences in this century. Although systems are composed of matters, the essence of system lies in dynamics and it cannot be described merely by enumerating components of the system.

At the same time, it is misleading to believe that only system structure, such as network topologies, is important without paying sufficient attention to diversities and functionalities of components. Although systems are composed of matters, the essence of system lies in dynamics and it cannot be described merely by enumerating components of the system. Unfortunately, molecular biology has just started at that time, so that only phenomenological analysis has been possible. Kitano, Systems Biology brief overview, Science, 29516621664, Systems Biology English Systems biology is an emergent field that aims at systemlevel understanding of biological systems.

Unfortunately, molecular biology has just started at that time, so

With the progress of genome sequence project and range of other molecular biology project that accumulate indepth knowledge of molecular nature of biological system, we are at the stage to seriously look into possibility of systemlevel understanding solidly grounded on molecularlevel understanding.What does it mean to understand at system level? Unlike molecular biology which focus on molecules, such as sequence of nucleotide acids and proteins, systems biology focus on systems that are composed of matters, the essence of system lies in dynamics and it cannot be described merely by enumerating components of the system.

It was only recently that systemlevel analysis can be grounded on discoveries at molecularlevel. Systems biology is in its infancy, but this is the area that we believe to be the main stream in biological sciences in this century. Kitano, Computational Systems Biology, Nature, 420206210, Cybernetics, for example, aims at describing animals and machines from the control and communication theory. Unfortunately, molecular biology has just started at that time, so that only phenomenological analysis has been possible. Both structure of the system, are key milestones to judge how much we understand the system.